Project Title: Bioassay development and effect-based chemical screening
Scope of Research:
The research involves the application of existing and novel bioassays to assess the risk of vertebrate endocrine disruption and other adverse health effects associated with exposure to chemicals in the environment. The development of in vitro and in vivo bioassays through genetic engineering will be a key component of the research. The model organisms applied as source of biomarkers or host of reporter constructs will include microbes and aquatic vertebrates. The bioassay testing will be performed in combination with analytical chemistry as part of various interdisciplinary projects related to water quality and water treatment technologies. The postdoctoral candidate will have the opportunity to work on their individual research as well as to work within a team (Doctoral and Masters level students), and in addition, to gain experience in supervision as well as project management.
Host: Department of Microbiology and Stellenbosch University Water Institute.
Requirements: PhD (must have graduated within the last five years)
• Previous experience in the technical expertise necessary for chemical and biological water quality monitoring, wastewater treatment, and organic and inorganic chemistry.
• A strong molecular biology background is required including experience in tissue culture and genetic engineering techniques such as CRISPR, TALEN or transposon mediated gene delivery.
• Proficiency in water quality assessment using bioassays as source of biomarkers, reporter gene assays, and in vivo animal exposures will be beneficial. Additionally, previous experience in independent project design and management must be demonstrated. Familiarity with the wastewater industry, environmental policy and management, student supervision, and communication between governmental, industrial and academic role players.
Postdoctoral research fellows are not eligible for employee benefits since they are registered as research fellows and their bursaries are awarded tax-free.
Commencement of duties: As soon as possible
Closing date: 26 April 2024
Enquiries: Send a letter of application, accompanied by a comprehensive curriculum vitae, including list of publications and the names and contact details of at least two referees, to Prof. Gideon Wolfaardt at This email address is being protected from spambots. You need JavaScript enabled to view it.
